| Date | Location | Result | |
| Apr 29, 2022 | Birmingham, Mich. | Kent State 16, Detroit Mercy 15 | Box score |
| Apr 23, 2022 | Akron, Ohio | Detroit Mercy 14, Akron 8 | Box score |
| Apr 16, 2022 | Birminbgham, MI | Youngstown State 10, Detroit Mercy 9 | Box score |
| Apr 09, 2022 | Mount Pleasant, Mich | Central Michigan 18, Detroit Mercy 9 | Box score |
| Apr 05, 2022 | South Bend, Ind. | Notre Dame 27, Detroit Mercy 2 | Box score |
| Apr 02, 2022 | Birmingham, MI | Robert Morris 13, Detroit Mercy 8 | Box score |
| Mar 26, 2022 | Kent, Ohio | Kent State 16, Detroit Mercy 11 | Box score |
| Mar 20, 2022 | Birmingham, Mich. | St. Bonaventure 18, Detroit Mercy 17 | Box score |
| Mar 16, 2022 | Birmingham, Mich. | Detroit Mercy 15, Akron 12 | Box score |
| Mar 12, 2022 | Youngstown, Ohio | Youngstown State 12, Detroit Mercy 11 | Box score |
| Mar 06, 2022 | Indianapolis, Ind. | Butler 18, Detroit Mercy 5 | Box score |
| Mar 2, 2022 | Birmingham, Mich. | Central Michigan 18, Detroit Mercy 6 | Box score |
| Feb 25, 2022 | Pontiac, Mich. | Marquette 22, Detroit Mercy 9 | Box score |
| Feb 23, 2022 | Pittsburgh, Pa. | Robert Morris 17, Detroit Mercy 9 | Box score |
| Feb 11, 2022 | Pontiac, Mich. | Michigan 23, Detroit Mercy 2 | Box score |